Is CLDI Worth Buying in 2026?

Calidi Biotherapeutics, Inc.

STOCK BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES) Updated 2026-07-26

Here’s whether Calidi Biotherapeutics, Inc. (CLDI) is worth buying in 2026 — based on weekly-updated price trend, RSI momentum, and return vs. the S&P 500. Our current read: Bearish.

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Bearish

Concerns: trading below the 200-day MA (long-term downtrend); below the 50-day MA (medium-term momentum negative); 50-day MA is falling (-11.06% over 10 days); RSI 21 — oversold; weak 1-year return of -98.9%; 3-month momentum negative (-55.8%); rising volume on a downtrend (distribution, 1.64x avg). Currently 99.1% off its 52-week high. Score: -7/7.

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CLDI is trading below its 200-day MA ($0.74) — a key warning sign the longer-term trend is under pressure. An RSI of 20.8 has dropped into oversold territory, which has historically preceded short-term bounces. The 1-year return of -98.9% compares to +20.4% for SPY (trailed the market by 119.3%). The current 99.1% drawdown from the 52-week high reflects elevated risk for momentum-based strategies.

$10,000 invested 1 year ago → $108 today
vs. S&P 500 (SPY) — same period trailed market by 119.3%

1-Year Price Chart

Daily candles
MA-50 MA-200 Up Down

Signal Check

Above 200-day MA ($0.74)
Above 50-day MA ($0.16)
!RSI(14) neutral zone (30–70) — currently 20.8
Positive return (-98.9%)
!Within 10% of period high (−99.1%)
Period Range $0.10
$0.10 $10.92
RSI (14) 20.8
0 · OversoldOverbought · 100

Key Metrics

Price$0.10
Period Return-98.9%
Period High$10.92
Period Low$0.10
Drawdown−99.1%
MA-50$0.16
MA-200$0.74
RSI (14)20.8
Avg Volume (30d)7.0M
vs. SPYtrailed by 115.4%
Return Rank#1240 of 1252

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