Is ESPR Worth Buying in 2026?

Esperion Therapeutics, Inc.

STOCK PHARMACEUTICAL PREPARATIONS Updated 2026-04-19

Here’s whether Esperion Therapeutics, Inc. (ESPR) is worth buying in 2026 — based on weekly-updated price trend, RSI momentum, and return vs. the S&P 500. Our current read: Bearish.

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Bearish

Positives: strong 1-year return of +111.6%. Concerns: trading below the 200-day MA (long-term downtrend); below the 50-day MA (medium-term momentum negative); 50-day MA is falling (-7.71% over 10 days); RSI 23 — oversold; 3-month momentum negative (-32.9%); rising volume on a downtrend (distribution, 1.30x avg). Currently 51.1% off its 52-week high. Score: -5/7.

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ESPR is trading below its 200-day MA ($2.75) — a key warning sign the longer-term trend is under pressure. An RSI of 23.1 has dropped into oversold territory, which has historically preceded short-term bounces. The 1-year return of +111.6% compares to +35.1% for SPY (beat the market by 76.5%). The current 51.1% drawdown from the 52-week high reflects elevated risk for momentum-based strategies.

$10,000 invested 1 year ago → $21,164 today
vs. S&P 500 (SPY) — same period beat market by 76.5%

1-Year Price Chart

Daily candles
MA-50 MA-200 Up Down

Signal Check

Above 200-day MA ($2.75)
Above 50-day MA ($2.83)
!RSI(14) neutral zone (30–70) — currently 23.1
Positive return (+111.6%)
!Within 10% of period high (−51.1%)
Period Range $2.04
$0.69 $4.18
RSI (14) 23.1
0 · OversoldOverbought · 100

Key Metrics

Price$2.04
Period Return+111.6%
Period High$4.18
Period Low$0.69
Drawdown−51.1%
MA-50$2.83
MA-200$2.75
RSI (14)23.1
Avg Volume (30d)6.7M
vs. SPYbeat by 76.5%
Return Rank#190 of 996

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